TOXICOINFORMATICS

COMPUTER SOFTWARE USED FOR THE CREATION OF SCIENTIFIC METHODS, NAMELY, FOR COMPARING THE RELATIVE TOXICITY OF ONE COMPOUND TO ANOTHER BASED UPON MOLECULAR AND CELLULAR ASSAYS AND FOR COMPARING THE RESULTS OF IN-VITRO AND IN-VIVO TOXICOLOGY ASSAYS; FOR CONNECTING THE RELATIONSHIP BETWEEN THE STRUCTURE OF A COMPOUND AND ITS TOXIC POTENTIAL; FOR ESTABLISHING THE RELATIONSHIP BETWEEN TRADITIONAL TOXICOLOGY MEASUREMENT AND MOLECULAR TOXICOLOGY MEASUREMENTS, NAMELY, GENE EXPRESSION, PROTEIN EXPRESSION, AND SIGNAL TRANSDUCTION PATHWAYS; COMPUTER SOFTWARE USED FOR THE ACQUISITION AND EVALUATION OF COMPUTERIZED DATA AND INFORMATION OF STATISTICAL ANALYSIS IN THE FIELDS OF TOXICOLOGY, PHARMACOLOGY AND BIOTECHNOLOGY, NAMELY, MOLECULAR TOXICOLOGY TESTING, GENE EXPRESSION ANALYSIS AND CELLULAR MOLECULAR TOXICOLOGY ASSAYS; STATISTICAL COMPARATIVE SOFTWARE WITH GRAPHING CAPABILITIES FOR USE IN COMPARING RESULTS OF MOLECULAR TOXICOLOGY EXPERIMENTS FROM ONE DRUG TO A LARGE NUMBER OF OTHER DRUGS TO IDENTIFY COMPOUNDS MOST SIMILAR TO THE COMPOUND BEING TESTED IN AN ASSAY; ALSO USED TO MEASURE THE QUALITY AND ROBUSTNESS OF DATA GENERATED IN A PARTICULAR EXPERIMENT IN THE FIELD OF TOXICOLOGY SCREENING AND SAFETY ASSESSMENT OF CHEMICALS USED AS PHARMACEUTICAL AGENTS, HOUSEHOLD PRODUCTS, PESTICIDES OR FOODS