T R A N S K A R Y O T I C

PHARMACEUTICALS AND BIOLOGICS FOR USE IN THE TREATMENT OF GENETIC DISORDERS, CANCER, HEMATOLOGIC DISORDERS, ENDOCRINE DISORDERS, REPRODUCTIVE DYSFUNCTION, SHORT STATURE, DIABETES, METABOLIC DISORDERS, DISORDERS OF THE CENTRAL NERVOUS SYSTEM, GASTROINTESTINAL DISORDERS CARDIOVASCULAR DISORDERS, AUTOIMMUNE DISORDERS AND OTHER DISORDERS OF THE IMMUNE SYSTEM, INFECTIOUS DISEASES AND ENZYME DEFICIENCY DISEASES; GENETICALLY ALTERED CELLS AND CELL LINES FOR USE IN THE PRODUCTION OF HUMAN THERAPEUTIC PROTEINS, FOR MEDICAL DIAGNOSTIC USE, FOR USE IN THE TREATMENT OF A VARIETY OF DISEASES AND DISORDERS AND FOR IMPLANTATION INTO HUMAN PATIENTS