SIGNUM PHARMACEUTICALS

Pharmaceutical preparations, namely, preparations for treating metabolic disorders of diabetes and obesity; pharmaceutical preparations for the regulation of food intake by delivering bio-active compounds to the central nervous system; pharmaceutical preparations for the regulation of glucose production by delivering bio-active compounds to the central nervous system; pharmaceutical preparations used to modulate long-chain fatty acyl-CoA levels in the hypothalamus; pharmaceutical preparations used to agonize KATP channels in the hypothalamus; pharmaceutical preparations used to inhibit pyruvate dehydrogenase kinase (PDHK) in the hypothalamus; pharmaceutical preparations used to effect amino acid and other analyte sensing in the hypothalamus for the treatment of obesity and diabetes