PATIENT SIGNAL RATE

Computer application software for managing clinical trials for purposes including, but not limited to, Risk Based Monitoring, namely, software for conducting Risk Based Monitoring and related workflows while conducting clinical trials for pharmaceuticals and medical devices; Computer programs for using the internet and the world wide web; Computer programs for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Computer shareware for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Computer software for accessing information directories that may be downloaded from the global computer network; Computer software for application and database integration; Computer software for computer system and application development, deployment and management; Computer software for creating searchable databases of information and data; Computer software for providing an on-line database in the field of transaction processing to upload transactional data, provide statistical analysis, and produce notifications and reports; Computer software for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Computer software for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring that may be downloaded from a global computer network; Downloadable software in the nature of a mobile application for managing clinical trials for purposes of, but not limited to, conducting Risk Based Monitoring; Software for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring

Communication by electronic computer terminals; Communications via analogue and digital computer terminals; Computer aided transmission of information and images; Computer aided transmission of messages and images; Computer transmission of information accessed via a code or a terminal; Computer-aided transmission of messages and images; Electronic data interchange services in the field of healthcare transactions such as claims, eligibility, claim status, electronic remittance advice, prior authorizations, attachments and referrals that allow direct transaction and payment communications between healthcare providers and payers; Electronic data transmission; Electronic exchange of data stored in databases accessible via telecommunication networks; Electronic exchange of medical records across a nationwide health information network; Electronic transmission of data and documents via computer terminals and electronic devices; Electronic transmission of e-mail; Electronic transmission of e-mail for workflow related to the management of Clinical Trial Data for purposes including, but not limited to, conducting Risk Based Monitoring; Providing a web site for synchronous and asynchronous communication and for connection of physicians with their patients regardless of medical organization or geographic location; Providing access to an electronic exchange of medical records across a nationwide health information network; Providing instant messaging services; Providing multiple use access to global computer information networks for the transfer and dissemination of a wide range of information; Providing multiple-user access to data on the Internet in the field of Clinical Trials for pharmaceutical and medical device testing, including processes, workflow and analytical analysis of data using Risk Based Monitoring methodologies; Signal transmission for electronic commerce via telecommunication systems and data communication systems; Streaming of data; Transfer of data by telecommunications; Transmission and delivery of data related to Clinical Trials including processes related, but not limited to, conducting Risk Based Monitoring via the internet and other digital networks; Transmission of digital files

Application service provider, namely, hosting, managing, developing, analyzing, and maintaining applications, software, and web sites, of others in the fields of healthcare, benefits programs, employee productivity, risk management; Application service provider, namely, hosting, managing, developing, analyzing, and maintaining applications, software and web sites of others in the fields of managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Biotechnology research; Cloud computing featuring software for use in managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Computer code conversion for others; Computer network design and computer software design for the managing of clinical trials for purposes including, but not limited to, of conducting Risk Based Monitoring; Computer programming and software design; Computer programming services for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Computer programming services, namely, managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Computer project management services; Computer services, namely, acting as an application service provider in the field of information management to host computer application software for the purpose of managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Computer services, namely, acting as an application service provider in the field of knowledge management to host computer application software for the purpose of managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Computer services, namely, designing and implementing software to manage clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring of clinical trials for others; Computer services, namely, hosting an interactive web site that allows useres to manage clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Computer services, namely, hosting and maintaining an on-line web site for others for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Computer services, namely, providing virtual and non virtual application servers, web servers, file servers, co-location servers, load balancing servers, redundancy servers, media servers and database servers of variable capacity to third party computing and data storage facilities; Conducting clinical trials for others; Conducting research and clinical trials for others relating to medical devices and pharmaceuticals in the field of ophthalmology; Consultation in the field of health risk assessment, namely, prediction and assessment of health risks to public and private agencies, facilities, individuals and locations following an accidental or terrorist caused release of chemical, biological, radiological or nuclear materials; Consulting services for others in the field of design, planning, and implementation project management of clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Customizing computer software by adding fields and workflows to enable the management of clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Data conversion of computer program data or information; Data mining; Data warehousing; Design and development of computer software for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Design for others in the field of computer networks, software, and engineering for the managing of clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Design of computer databases; Design of computer networks and software for others for the managing of clinical trials and for purposes including, but not limited to, conducting Risk Based Monitoring; Electronic monitoring and reporting of data obtained by managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring using computers or sensors; Electronic storage of documents and archived e-mails; Electronic storage of data used in managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Electronic storage services for archiving databases, images and other electronic data; Electronic storage services for archiving electronic data; Installation and maintenance of software for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring software; Installation of software to manage clinical trials, including Risk Based Monitoring software; Integration of computer systems and networks; Internet-based application service provider, namely, hosting, managing, developing, analyzing, and maintaining the code, applications, and software for web sites of others; Laboratory research services relating to pharmaceuticals; Maintenance of computer software used for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Outsource service provider in the field of information technology consulting; Pharmaceutical products development; Platform as a service (PAAS) featuring computer software platforms for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Programming of computer software for others; Providing a members-only website featuring technology which provides members with the ability to manage clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing a secured-access, members only website featuring technology that gives members the ability to manage clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing a web site featuring technology that enables physicians to generate, manage and exchange medical information and documents regardless of medical organization or geographic location; Providing a website featuring educational information in the field of clinical research; Providing a website featuring information about investigational medical devices, diagnostics and drugs; Providing a website featuring non-downloadable software for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing a website featuring resources, namely, non-downloadable software for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring ; Providing a website featuring technology that enables users to managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing a website that gives computer users the ability to manage clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing an on-line searchable database in the field of clinical trials for pharmaceuticals and medical devices, and for purposes including, but not limited to, conducting Risk Based Monitoring for scientific research purposes; Providing an online non-downloadable Internet-based system application featuring technology enabling users to managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing medical and scientific research information in the field of clinical trials; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Providing on-line, non-downloadable, Internet-based software application for medical billing for physicians and health care institutions; Providing technology information in the field of managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing temporary use of a non-downloadable web application for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing temporary use of a web-based software application for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing temporary use of non-downloadable cloud-based software for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing temporary use of on-line non-downloadable cloud computing software for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing temporary use of on-line non-downloadable software and applications for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing temporary use of on-line non-downloadable software development tools for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing temporary use of on-line non-downloadable software for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Providing temporary use of online non-downloadable middleware for providing an interface between web browser and legacy systems; Providing temporary use of online non-downloadable middleware for providing an interface between systems used to conduct clinical trials and the reporting of information on the performance of pharmaceuticals and medical devices, including matters related to Risk Based Monitoring; Rental and maintenance of computer software; Rental of application software; Rental of computer software; Rental of computer software and programs; Software as a service (SAAS) services featuring software for managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Software as a service (SAAS) services, namely, hosting software for use by others for use managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Software development and product development in the field of managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Software development in the field of managing clinical trials for purposes including, but not limited to, conducting Risk Based Monitoring; Software porting; Technical consulting in the field of pharmaceutical studies; Technical support services, namely, 24/7 monitoring of network systems, servers and web and database applications and notification of related events and alerts; Temporary electronic storage of information and data; Updating and rental of software for data processing; Updating, design and rental of software