GASTROPLUS

Computer software, namely, computer software for modeling and the conducting of simulations of properties of drugs or chemicals including absorption, release rate, bioavailability, pharmacokinetics, and pharmacodynamics; computer software which allows for prediction of drug-to-drug interactions; computer software for the prediction of drug effects on animals and virtual patient populations; computer software which allows researchers to adjust pharmacodynamic models to observed data and to then use the resulting fitted models to predict pharmacodynamic changes due to changes in dose, dosage form, and dosing regimen of a drug or chemical; computer software which allows for the generation of in vitro-in vivo correlations; computer software which allows for the prediction of absorption and systemic distribution/elimination for large molecules