FLEXCELL

Cell culture plates having rigid or flexible bottoms for laboratory use; cell culture plates having splash minimizing rims; valved rubber stoppers for use with flexible bottomed culture plates to prevent flexing of the bottom; computer regulated vacuum units and pressure units to deform cells growing in culture in flexible bottomed culture plates; and flexible bottomed cell culture plates and associated molds and computer regulated vacuum units and pressure units to grow and mechanically condition three-dimensional cell constructs