Pharmaceutical preparations for the treatment of spasm; pharmaceutical preparations for treating dystonia; muscle relaxants; pharmaceutical preparations used in cosmetic surgery; pharmaceutical preparations containing botulinum toxin; botulinum toxin for medical use for use in the treatment of neuropathy pain; pharmaceutical preparations containing botulinum toxin for the treatment of wrinkles; pharmaceutical preparations containing botulinum toxin fragments for the treatment of wrinkles; bacterial toxins, namely, bacterial poisons; pharmacological preparations for skin care; biological preparations for pharmaceutical purposes for the treatment of neurological disorders, muscle dystonias, smooth muscle disorders, autonomic nerve disorders, headaches, wrinkles, hyperhydrosis and cerebral palsy; biological preparations for pharmaceutical purposes for the treatment of tremors, namely, spasmodic smooth, striated or cardiac muscles; pharmaceutical agents for epidermis; biological preparations for medical or veterinary purposes for the treatment of aesthetic dermatology, orthopaedics, arthritis and ophthalmology; bacteriological preparations for medical and veterinary use; adjuvants for medical purposes; medicines for human purpose, namely, medicines for skin care; pharmaceutical preparations for the treatment of wrinkles; pharmaceutical preparations for use in dermatology; botulinum toxin for medical use for use in the treatment of excessive sweating, excessive eye blinking, neuropathy pain, facial wrinkles, headache, pain, spasm, dystonia, urogenital system diseases and conditions, skin disorders; therapeutic drugs and agents for use in the treatment of excessive sweating, excessive eye blinking, neuropathy pain, facial wrinkles, headache, pain, spasm, dystonia, urogenital system diseases and conditions, skin disorders.