Medical apparatus and instruments for diabetes management use; medical apparatus and instruments for monitoring interstitial fluid glucose; sensor-based glucose monitors for medical purposes; continuous glucose monitoring systems primarily composed of medical apparatus for monitoring interstitial fluid glucose; medical diagnostic apparatus for determination of analyte concentrations; electrochemical sensors for determination of analyte concentrations in fluids for medical purposes; wearable sensors used to measure and provide information related to analyte concentrations in interstitial fluid for health purposes; medical apparatus for monitoring analyte concentrations in interstitial fluid; patient monitoring sensors for monitoring analyte concentrations; sensors for monitoring analyte concentrations for health purposes; patient monitoring sensors for determination of analyte concentrations in interstitial fluid; sensors for determination of analyte concentrations in interstitial fluid for health purposes