Human pharmaceuticals for the treatment of cancers, cardiovascular diseases, metabolic diseases, metabolic disorders, diabetes, hypertension, vascular diseases, pulmonary diseases, pulmonary conditions, bronchoconstrictive diseases, bronchoconstrictive conditions, gastrointestinal disorders, diseases and conditions associated with cardiac muscle dysfunction, cardiac muscle wasting, cardiac muscle atrophy, cardiac muscle weakness, infectious diseases; veterinary pharmaceuticals for the treatment of cancers, cardiovascular diseases, neurological diseases, neurological conditions, neuromuscular diseases, neuromuscular conditions, musculoskeletal disorders, metabolic diseases, metabolic disorders, diabetes, hypertension, vascular diseases, pulmonary diseases, pulmonary conditions, bronchoconstrictive diseases, bronchoconstrictive conditions, gastrointestinal disorders, diseases and conditions associated with cardiac muscle dysfunction, skeletal muscle dysfunction, cardiac muscle wasting, skeletal muscle wasting, cardiac muscle atrophy, skeletal muscle atrophy, cardiac muscle weakness, skeletal muscle weakness, infectious diseases